Featured Publications

 

Radiolabelling Method Development

 

2017

Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor

A Lebedev, J Jiao, J Lee, F Yang, N Allison, H Herschman, S Sadeghi ( 2017) Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor PloS one 12 (5), e0176606 PMCID:  PMC5413030

2017

An automated synthesizer for electrochemical 18F-fluorination of organic compounds

Waldmann CM, Lebedev A, Allison N, Sadeghi S. (2017) An automated synthesizer for electrochemical 18F-fluorination of organic compounds. Appl Radiat Isot.

 

Diagnostic Radiopharmceuticals

 

2019

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

Momcilovic M, Jones A, Bailey S, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB (2019) In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature  (575), 380–384 PMID: 31666695

2018

In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures

Johann Le Floc’h , Aimen Zlitni, Holly A. Bilton, Melissa Yin, Arash Farhadi, Nancy R. Janzen, Mikhail G. Shapiro, John F. Valliant, F. Stuart Foster. Mol. Imaging Biol. 2018; 20:230-239. DOI: 10.1007/s11307-017-1122-6.

2017

Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer

Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. (2017) Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep.18(3):601-610. PMID: 28099841; PMCID: PMC5260616.

2017

Preparation of an 18F-Labeled Hydrocyanine Dye as a Multimodal Probe for Reactive Oxygen Species

Salma Al-Karmi, Silvia A. Albu, Alyssa Vito, Nancy Janzen, Shannon Czorny, Laura Banevicius, Max Nanao, Jon Zubieta, Alfredo Capretta, John F Valliant,   From Chemistry - A European Journal 2017, 23(2), 254-258.

2017

67Ga-labeled deferoxamine derivatives for imaging bacterial infection: Preparation and screening of functionalized siderophore complexes

Joseph A. Ioppolo, Deanna Caldwell, Omid Beiraghi, Lisset Llano, Megan Blacker, John F. Valliant, Paul J Berti.   From Nuclear Medicine and Biology 2017, 52, 32-41.  | Language: English, Database: CAPLUS

2017

Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: The Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile

Vincent Bouvet, Melinda Wuest, Justin J. Bailey, Cody Bergman, Nancy Janzen, John F. Valliant, Frank Wuest.   From Molecular Imaging and Biology 2017, 19(6), 923-932

 

Bio-orthogonal Chemistry 

 

2017

Preparation of tetrazine-containing [2 + 1] complexes of 99mTc and in vivo targeting using bioorthogonal inverse electron demand Diels-Alder chemistry

Abdolreza Yazdani, Nancy Janzen, Shannon Czorny, Robert G. Ungard, Tanya Miladinovic, Gurmit Singh, John F. Valliant.  From Dalton Transactions 2017, 46(42), 14691-14699.

 

Therapeutic Radiopharmaceuticals

 

Exciting Therapeutic Radiopharmaceutical Publications Coming Soon!

 

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