Featured Publications
Radiolabelling Method Development
2020
Imidazole fused phenanthroline (PIP) ligands for the preparation of multimodal Re(i) and 99mTc(i) probes
Slikboer et al., “Imidazole Fused Phenanthroline (PIP) Ligands for the Preparation of Multimodal Re(I) and 99mTc(I) Probes.” Dalton Transactions. 2020.
2017
Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor
A Lebedev, J Jiao, J Lee, F Yang, N Allison, H Herschman, S Sadeghi ( 2017) Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor PloS one 12 (5), e0176606 PMCID: PMC5413030
2017
An automated synthesizer for electrochemical 18F-fluorination of organic compounds
Waldmann CM, Lebedev A, Allison N, Sadeghi S. (2017) An automated synthesizer for electrochemical 18F-fluorination of organic compounds. Appl Radiat Isot.
Diagnostic Radiopharmceuticals
2020
99mTc-Functionalized Single-Walled Carbon Nanotubes for Bone Targeting
Afaf R. Genady, Darryl Fong, Samantha R. Slikboer, Mohamed E. El-Zaria, Rowan Swann, Nancy Janzen, Amber Faraday, Stuart A. McNelles, Mojgan Rezvani, Saman Sadeghi, Alex Adronov, and John F. Valliant
2019
In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer
Momcilovic M, Jones A, Bailey S, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB (2019) In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature (575), 380–384 PMID: 31666695
2018
In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures
Johann Le Floc’h , Aimen Zlitni, Holly A. Bilton, Melissa Yin, Arash Farhadi, Nancy R. Janzen, Mikhail G. Shapiro, John F. Valliant, F. Stuart Foster. Mol. Imaging Biol. 2018; 20:230-239. DOI: 10.1007/s11307-017-1122-6.
2017
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. (2017) Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep.18(3):601-610. PMID: 28099841; PMCID: PMC5260616.
2017
Preparation of an 18F-Labeled Hydrocyanine Dye as a Multimodal Probe for Reactive Oxygen Species
Salma Al-Karmi, Silvia A. Albu, Alyssa Vito, Nancy Janzen, Shannon Czorny, Laura Banevicius, Max Nanao, Jon Zubieta, Alfredo Capretta, John F Valliant, From Chemistry - A European Journal 2017, 23(2), 254-258.
2017
67Ga-labeled deferoxamine derivatives for imaging bacterial infection: Preparation and screening of functionalized siderophore complexes
Joseph A. Ioppolo, Deanna Caldwell, Omid Beiraghi, Lisset Llano, Megan Blacker, John F. Valliant, Paul J Berti. From Nuclear Medicine and Biology 2017, 52, 32-41. | Language: English, Database: CAPLUS
2017
Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: The Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile
Vincent Bouvet, Melinda Wuest, Justin J. Bailey, Cody Bergman, Nancy Janzen, John F. Valliant, Frank Wuest. From Molecular Imaging and Biology 2017, 19(6), 923-932
Bio-orthogonal Chemistry
2020
Tetrazine-Derived Near-Infrared Dye as a Facile Reagent for Developing Targeted Photoacoustic Imaging Agents
Slikboer et al. Tetrazine-Derived Near-Infrared Dye as a Facile Reagent for Developing Targeted Photoacoustic Imaging Agents,
Mol. Pharmaceutics 2020, 17, 3369−3377
2017
Preparation of tetrazine-containing [2 + 1] complexes of 99mTc and in vivo targeting using bioorthogonal inverse electron demand Diels-Alder chemistry
Abdolreza Yazdani, Nancy Janzen, Shannon Czorny, Robert G. Ungard, Tanya Miladinovic, Gurmit Singh, John F. Valliant. From Dalton Transactions 2017, 46(42), 14691-14699.